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Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl-

2-METHYL-5-TRIFLUOROMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID

CAS: 128694-63-3

Molecular Formula: C6H5F3N2O2

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Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl- - Names and Identifiers

Name 2-METHYL-5-TRIFLUOROMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID
Synonyms EU-0083300
MLS000850704
SMR000456721
TimTec1_003188
2-methyl-5-(trifluoromethyl)pyrazole-3-carboxylic acid
2-methyl-5-(trifluoromethyl)-3-pyrazolecarboxylic acid
2-METHYL-5-TRIFLUOROMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID
1-Methyl-3-trifluoromethyl-1H-pyrazole-5-carboxylic acid
Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl-
1-Methyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid
1H-Pyrazole-5-carboxylic acid, 1-methyl-3-(trifluoromethyl)-
CAS 128694-63-3
EINECS 673-161-3
InChI InChI=1/C6H5F3N2O2/c1-11-3(5(12)13)2-4(10-11)6(7,8)9/h2H,1H3,(H,12,13)

Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl- - Physico-chemical Properties

Molecular FormulaC6H5F3N2O2
Molar Mass194.11
Density1.56±0.1 g/cm3(Predicted)
Melting Point131-133℃
Boling Point288.8±40.0 °C(Predicted)
Flash Point128.4°C
Vapor Presure0.00106mmHg at 25°C
pKa2.55±0.25(Predicted)
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.497

Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl- - Risk and Safety

Risk CodesR22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
HS Code29331990
Hazard ClassIRRITANT

Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl- - Reference Information

introduction 2-methyl -5 trifluoromethyl-2H-pyrazole -3-carboxylic acid is a derivative of pyrazole carboxylic acid, which has attracted more and more attention from researchers of pharmaceutical and chemical intermediates.
Preparation 2-methyl-5trifluoromethyl-2H-pyrazol-3-carboxylic acid is an intermediate for the synthesis of a drug for the treatment of cardiovascular diseases. It is reported that it is composed of diethyl oxalate and 2-pentanone through the condensation reaction of claisen esters, cyclization with hydrazine hydrate, methylation reaction, and hydrolysis reaction. The synthesis roadmap of 2-methyl -5 trifluoromethyl-2H-pyrazol-3-carboxylic acid is as follows:
Last Update:2024-04-09 02:00:06
Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl-
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 2-Methyl-5-Trifluoromethyl-2H-Pyrazole-3-Carboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 128694-63-3
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Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
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Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: 2-Methyl-5-Trifluoromethyl-2H-Pyrazole-3-Carboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 128694-63-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 2-Methyl-5-Trifluoromethyl-2H-Pyrazole-3-Carboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 128694-63-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Pyrazole-5-carboxylic acid, 3-trifluorromethyl-1-methyl-
2-乙酰胺-5-溴噻唑
S-3-羟基吡咯烷盐酸盐
4-Oxazolecarboxylic acid, 2-[2-[(cyclopropylmethyl)[(1,1-dimethylethoxy)carbonyl]amino]-4-pyridinyl]-
1-乙基-苯并咪唑啉酮
CCRIS 5464
1-[(2-CHLORO-1,3-THIAZOL-5-YL)METHYL]-1H-PYRROLE-2-CARBALDEHYDE
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